Novel Coronavirus (2019-nCoV)
Brief Description
Novel Coronavirus (2019-nCoV) Polymerase Chain Reaction (PCR)
SARS-CoV-2 Antigen
SARS-CoV-2 TrimericS IgG semi-quantitative Serology*
* The LIAISON® SARS-CoV-2 Antigen test and TrimericS IgG are only for use under the Food and Drug Administration's Emergency Use Authorization.
Laboratory Unit
Molecular
Virology
Methodology
Real-Time PCR
Chemiluminescent Immunoassay (CLIA)
Specimen Collection
2019-nCoV Collection Kits
SARS-CoV-2 IgG Collection Kits
SARS-CoV-2 Antigen Collection Kits
Before collecting and shipping specimens for Novel Coronavirus (2019-nCoV) testing, call the Missouri Department of Health and Senior Services at 877-435-8411 for approval.
Note that before any specimen is sent for testing, DHSS staff must first be consulted!
After consultation and determination that the patient meets the criteria for testing, contact the Missouri State Public Health Laboratory (MSPHL) at 573/751-3334 or 800/392-0272 if you have questions regarding collection and shipping prior to collecting the specimens. This will help ensure that proper specimens are obtained in the right quantity, and that they are packed and transported properly.
Storage/Transport
Store and ship at refrigerated temperature
Serology – Shipped within 21 days of collection
Antigen – Received within 6 days of collection
GIS map of courier drop off locations Monday-Friday
List of courier drop off locations by county Monday-Friday
COVID-19 Kit Instructions
SARS-CoV-2 IgG Serology Kit Instructions
SARS-CoV-2 Antigen Kit Instructions
Acceptable Specimen Type(s)
Real-Time PCR
- Nasopharyngeal swab in Viral Transport Media (VTM)
- Nasal swab in provided inactivation buffer
Antigen
- Nasal swab in provided inactivation buffer
IgG Serology (Collected 15 days or more post symptom onset)
- Serum (preferred)
- Plasma (lithium heparin and dipotassium EDTA)
Test Request Form(s)
Possible Results
Real-Time PCR
- Detected*
- Not Detected
- Invalid (Specimen is inadequate for testing, a new specimen may need to be collected)
Antigen
- Positive
- Negative
- Invalid (Specimen is inadequate for testing, a new specimen may need to be collected)
IgG Serology
- Positive – antibody level expressed as AU/ml
- Negative
- Invalid (Specimen is inadequate for testing, a new specimen may need to be collected)
* Effective October 1, 2021, all specimens submitted for SARS-CoV-2 Real-Time PCR analysis will also receive testing for Influenza A & B by Real-Time PCR analysis.
Unacceptable Conditions
- The name on the specimen does not match the name on the requisition form.
- The specimen container is not labeled with the patient’s name.
- Improper storage/transport of specimen.
- The sample collected with improper collection device—cotton-tipped or calcium-alginate swab, wooden-shaft swab, transport media not intended for viruses.
- The specimen is not one of the listed acceptable specimens.
- Quantity Not Sufficient for testing
- Hemolyzed specimen
Interfering Substances
Cotton-tipped or calcium-alginate swab, wooden-shaft swab, transport media not intended for viruses
Result Reported
PCR - Testing is performed and results are reported the same day the specimen is received.
Fees
None
CPT Codes
N/A
LOINC/SNOMED Codes
N/A
Additional Information
- CDC Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay Fact Sheet for Patients
- CDC Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay Fact Sheet for Healthcare Providers
- CDC Novel Coronavirus (2019-nCoV) Website
- DiaSorin Fact sheet for Healthcare providers – Serology
- DiaSorin Fact sheet for Recipients – Serology
- DiaSorin Letter of Authorization – Serology
- DiaSorin Fact sheet for Healthcare providers – Antigen
- DiaSorin Fact sheet for Recipients – Antigen
- DiaSorin Letter of Authorization – Antigen
- CDC Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay FDA Letter of Authorization