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Immunization Laws and Regulations

Contact Information

Bureau of Immunizations
Missouri Department of Health and Senior Services
PO Box 570
930 Wildwood Dr
Jefferson City, MO 65102-0570


Phone: 573-751-6124
Toll-Free: 800-219-3224
Fax: 573-526-0238
Email: Immunization@health.mo.gov


VFC - ShowMeVax Helpdesk
Toll-Free: 866-256-3166
Fax: 573-526-5220
Email: vfc-smvsupport@health.mo.gov


Vaccines for Children Program (VFC)
Phone: 800-219-3224
Fax: 573-526-0238

Vaccines for Children Regional Contacts

This page from the Missouri Department of Health & Senior Services provides a centralized directory of state statutes and regulations governing immunization requirements for schools, daycares, and healthcare providers. It includes specific legal links regarding vaccine safety, mandatory reporting, and the ShowMeVax registry.

Thimerosal Statute


191.235 Mercury Contained in Immunizations and Exemptions

Missouri Immunization Statutes


167.181 Immunization of School Children

167.182 HPV Informational Brochure

167.183 Disclosure of Immunization Records

167.191 Contagious Diseases Excluded from School

174.335 Meningococcal disease, all on-campus students provided information on--election to receive vaccination--records to be maintained.

192.072 Educational Materials to be Developed by the Bureau of Immunization

192.630 Advisory Committee on Childhood Immunization

210.003 Immunization of Children in Day Care

334.157 Hepatitis B Vaccine Regulation by the State Board of Registration for the Healing Arts

338.010 Mandated Immunization Reporting for Pharmacies

376.1215 Mandated Immunization Coverage

431.058 Consent to Immunization of a Child

431.061.1 Immunization Consent

Blood Tests for Pregnant Women


Immunization and the Code of State Regulations


The Code of State Regulations, or rules, is available on the Missouri Secretary of State’s web site in PDF format. Regulations are organized by title, division, chapter, and section. For example, 19 CSR 20-20.020 refers to Title 19, Division 20, Chapter 20, Section 020. The links that follow take the user to the appropriate division and chapter of the regulations. Scroll to the specific section number.

19 CSR 20-20.020 Reporting Communicable, Environmental and Occupational Diseases

19 CSR 20-20.030 Exclusion from School and Readmission

19 CSR 20-20.040 Measures from the Control of Communicable, Environmental and Occupational Diseases

19 CSR 20-28.010 Immunization Requirements for School Children

19 CSR 20-28.030 Distribution of Childhood Vaccines

19 CSR 20-28.040 Day Care Immunization Rule

19 CSR 20-28.060 Minimum Immunization Coverage to be Provided by Individual and Group Health Insurance Policies

Administration of Influenza Vaccines Per Protocol