Birth Defects
Birth defects are the leading cause of infant mortality, and the costs, both monetary and non-monetary, to individuals, families, communities, and the health care industry are substantial. Nationally, there are 120,000 babies (about 1 in 33) born with a birth defect each year.
Folic acid contributes to overall good health and is particularly important for women of childbearing age. Insufficient folic acid is a major cause of serious birth defects involving the spine and brain (neural tube defects). Some studies suggest that folic acid may also reduce a baby’s risk of other birth defects, such as orofacial clefts, heart defects and urinary defects. Folic acid may also help protect women and men from cardiovascular disease and some cancers, including cervical, colon, and breast.
Precautions to Take While Pregnant
During pregnancy, a woman may be exposed to various infectious diseases, some of which have the ability to infect the placenta and seriously harm a fetus resulting in deafness, vision loss, neurological and behavioral disorders, or other birth defects. Toxoplasmosis, cytomegalovirus (CMV), varicella, rubella, and lymphocytic choriomeningitis virus (LCMV) are among the agents that are recognized to have the potential to cause birth defects in a developing fetus. Additionally, while some infectious diseases may not pass from an infected mother to her baby, they may have a serious impact on pregnancy such as uterine infection, miscarriage, premature labor, or stillbirth.
Prenatal testing for immunity to infections is an ideal start for any woman planning a family. Furthermore, should exposure to infectious disease occur while a woman is pregnant, she should be aware that consultation with her physician is important to determine the likelihood of infection or harm to the fetus, and the preventive measures available such as vaccination.
Learn more about the common infections that pregnant women can have that may cause serious birth defects in a developing baby click on the following link Pregnancy | CDC.
Missouri statute related to prenatally diagnosed conditions - RSMo 191.923
Missouri Hospitals and Specialty Clinics
Eastern Region:
          SSM Health Cardinal Glennon  Children’s Hospital – Pediatric Genetics
          St. Louis Children’s Hospital –  Genetics and Genomic Medicine 
          Washington University School of Medicine – Genetics and  Genomic Medicine 
          SSM Health Cardinal Glennon St.  Louis – Fetal Care Institute 
          Maternal & Fetal Care at SSM  Health St. Mary’s Hospital – St. Louis 
          Mercy Maternal Fetal Medicine 
          Barnes-Jewish Hospital – Women &  Infants Center 
          SSM Health Cardinal Glennon - St.  Louis Cleft-Craniofacial Center 
          St. Louis Children’s Hospital – Down  Syndrome Center
          Washington University School of  Medicine – Huntington’s Disease Center of Excellence
          St. Louis Children’s Hospital –  Neurofibromatosis Clinical Program 
          SSM Health Cardinal Glennon  Children’s Hospital - Neurofibromatosis
Central Region:
          University of Missouri Health Care –  Children’s Health 
          University of Missouri Health Care –  Maternal Fetal Care Center 
          University  of Missouri Health Care - Thompson Center for Autism & Neurodevelopmental  Disorders
          University of Missouri Health Care –  Pediatric Craniofacial Syndromes 
          University of Missouri Health Care –  Movement Disorders 
Western Region:
          Children’s Mercy Kansas City –  Genetics Clinic 
          Children’s Mercy Kansas City – Fetal  Health Center 
          Children’s Mercy Kansas City – Cleft  and Craniofacial Clinic
          Children’s Mercy Kansas City – Down  Syndrome Clinic
State Resources
National Resources
National Down Syndrome Congress  (NDSC)
          March of Dimes
          National Birth Defects Prevention Network
          Spina Bifida  Association  
          Easter  Seals 
          National Center on Birth Defects and  Developmental Disabilities
          National Institutes of Health  
          National Institute of Neurological  Disorders and Stroke
          National Library of  Medicine
        The Arc of the United States
        National Center for Hearing Assessment and Management
        National Organization for Rare Disorders (NORD)
        Stickler Involved People (SIP)
        Support Organization For Trisomy 18, 13 and Related  disorders
        CDC Pregnancy Information
        CDC Folic Acid