The Missouri Healthcare-Associated Infection Reporting System (MHIRS) site has been developed to provide information to healthcare providers on the Missouri Department of Health and Senior Services (DHSS) reporting requirements for healthcare-associated infections. With the passage of the Missouri Nosocomial Infection Control Act of 2004, hospitals and ambulatory surgery centers are required to report healthcare-associated infections to the DHSS. (For additional information on the statute and related rules, see Laws and Regulations.)