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Application Resources - Microbusiness

Division of Cannabis Regulation
PO Box 570
Jefferson City, MO 65102-0570
Toll-Free Access Line: 866-219-0165
(9:00 am – 4:00 pm CST Monday – Friday)

The call center will close at 2:45pm on Wednesday, October 28, 2026 for a staff meeting.

The call center will be closed on the last Friday of each month from 9:00 AM to 10:00 AM for a mandatory staff meeting.

Email for general inquiries:
Cannabisinfo@health.mo.gov
 

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DCR Functional Listing

Application Window Closed

The microbusiness application window has closed as of July 28, 2026. The department will verify that submitted applications meet minimum requirements for the lottery drawing on September 9th, 2026.

Application Tutorials

Need assistance with navigating the online registry portal? The application tutorials provide step-by-step guidance to complete and submit a microbusiness application.

Eligibility Tools

To apply for a cannabis microbusiness license in Missouri, individuals who will be majority owners must meet at least one of the eligibility criteria outlined in Article XIV, Section 2 of the Missouri Constitution. The Division of Cannabis Regulation (DCR) provides an online dashboard listing Missouri ZIP codes and census tracts that meet the microbusiness program eligibility criteria for unemployment and poverty rates, unaccredited school districts and historic rate of marijuana-related incarceration.