These following documents are in draft form and have not been approved by the department to begin the formal rulemaking process to establish a new rule or amend an existing rule. The purpose of providing these drafts to the public, and seeking feedback, is to obtain feedback and work with stakeholders in a collaborative way to increase our understanding of potential impacts, provide clarity regarding the intended objective and work to resolve issues prior to the formal rulemaking process.

Regulation Summary Draft
Language
Fiscal Note(s) Deadline for Comments Comments

19 CSR 100-1.060

Cannabis Regulation

The amendment adds application requirements to ensure consistency between rule, Constitutional requirements, and license applications. This amendment also adds requirements for applying for and being approved for microbusiness licensure to address concerns that arose during the first two rounds of microbusiness license issuance.

Proposed Amendment

N/A Aug. 21, 2025 Submit

19 CSR 100-1.100

Cannabis Regulation

The amendment improves cannabis license operations by removing the 50% threshold for preapproval of ownership changes and replacing it with an annual review of ownership percentages, establishing a framework for approval of publicly traded companies’ ownership in cannabis licenses and clarifying document requirements. This amendment also clarifies the recall procedure for cannabis product unable to be traced to cannabis grown in Missouri and addresses how ownership ineligibility or prior violations of rules may affect individuals’ or entities’ participation in the regulated marijuana industry.

Proposed Amendment

N/A Aug. 21, 2025 Submit

19 CSR 100-1.190

Cannabis Regulation

The amendment adds clarification about what the Division of Cannabis Regulation expects for application, ownership, and operation of a microbusiness license in order to address concerns that arose during the first two rounds of microbusiness license issuance.

Proposed Amendment

N/A Aug. 21, 2025 Submit

19 CSR 100-1.200

Cannabis Regulation

This proposal intends to establish licenses to perform cannabis research in Missouri. The rule describes what a cannabis research license is authorized to do and the application requirements for such a license. Under Article XIV, Section 2 of the Missouri Constitution, the Department of Health and Senior Services has the authority to create and issue additional licenses intended to facilitate scientific research or education.

Proposed Rule

N/A Aug. 21, 2025 Submit

19 CSR 30-1.002

The amendment (emergency and proposed amendment) updates the Schedules of Controlled Substances to be consistent with 21 CFR Part 1308. The amendment updates the rule to reflect changes made to the federal controlled substance schedule since the rule was last updated in September of 2024. This is an existing regulation but needs to be updated to reflect DEA Scheduling Actions.

Section 195.015, RSMo charges the department with similarly scheduling controlled substances as they are controlled under federal law. Section 195.015.4 requires the Department of Health and Senior Services to submit emergency rules to the Secretary of State within thirty days of a federal scheduling action to allow for similar inclusion, rescheduling, or deletion of controlled substances with this schedule.

Emergency Amendment

Proposed Amendment

N/A Aug. 29, 2025 Submit