Newborn Blood Spot Screening Panel

Missouri law mandates newborn blood spot screening for all infants. The goal of the Newborn Blood Spot Screening Program is to identify infants at risk and in need of diagnostic testing for the disorders listed below. Infants with positive newborn screen results for a particular condition are followed up to ensure that confirmatory testing is done. Infants found to be positive are entered into a system of medical care. A normal screening result does NOT rule out the possibility of an underlying metabolic/genetic/endocrine disease.

As of Jan. 1, 2017, Missouri's Newborn Blood Spot Screening Panel includes the following disorders:


Amino Acid Disorders


Fatty Acid Oxidation Disorders


Organic Acid Disorders

Hemoglobinopathies

Lysosomal Storage Disorders

* There is a lower probability of detection of this disorder during the immediate newborn period.
** Currently conducting statewide pilot/implementation testing.